• Scott, JB, Ward, CL, Corona, BT, Deschenes, MR, Harrison, BS, Saul, JM, Christ, GJ. 2016. Achieving Acetylcholine Receptor Clustering in Tissue-Engineered Skeletal Muscle Constructs In vitro through a Materials-Directed Agrin Delivery Approach. Front Pharmacol 7:508.
  • Christ, GJ. 2016. Introduction. Cells Tissues Organs (Print) 202:141-142.
  • Passipieri, JA, Christ, GJ. 2016. The Potential of Combination Therapeutics for More Complete Repair of Volumetric Muscle Loss Injuries: The Role of Exogenous Growth Factors and/or Progenitor Cells in Implantable Skeletal Muscle Tissue Engineering Technologies. Cells Tissues Organs (Print) 202:202-213.
  • Mintz, EL, Passipieri, JA, Lovell, DY, Christ, GJ. 2016. Applications of In Vivo Functional Testing of the Rat Tibialis Anterior for Evaluating Tissue Engineered Skeletal Muscle Repair. J Vis Exp
  • Burmeister, D, et al, Christ, GJ. The potential utility of non-invasive imaging to monitor restoration of bladder structure and function following subtotal cystectomy (STC). BMC Urol. 2015 Oct 14;15:103.
  • Christ, GJ, Passipieri, J, Treasure, T, Freeman, P, Wong, M, Martin, NRW, Player, D, Lewis, MP. Chapter 43: Skeletal Muscle Tissue Engineering, p. 567-592, In: Stem Cell Biology and Tissue Engineering in Dental Science, Vishwakarma & Sharp, Eds. Elsevier, 2014.
  • Zhao, W, Ju, YM, Christ, G, Atala, A, Yoo, JJ, Lee, SJ. Diaphragmatic muscle reconstruction with an aligned electrospun poly(ε-caprolactone)/collagen hybrid scaffold. Biomaterials. 2013 Nov;34(33):8235-40.

2012 and earlier

  1. Criswell, TL, Corona, BT, Wang, Z, Zhou, Y, Niu, G, Xu, Y, Christ, GJ, Soker, S. 2013. The role of endothelial cells in myofiber differentiation and the vascularization and innervation of bioengineered muscle tissue in vivo. Biomaterials 34:140-9.
  2. Tillman, BW, Yazdani, SK, Neff, LP, Corriere, MA, Christ, GJ, Soker, S, Atala, A, Geary, RL, Yoo, JJ. 2012. Bioengineered vascular access maintains structural integrity in response to arteriovenous flow and repeated needle puncture. J Vasc Surg 56:783-93.
  3. Burmeister, D, AbouShwareb, T, D'Agostino, R Jr, Andersson, KE, Christ, GJ. 2012. Impact of partial urethral obstruction on bladder function: time-dependent changes and functional correlates of altered expression of Ca²⁺ signaling regulators. Am J Physiol Renal Physiol 302:F1517-28.
  4. Corona, BT, Machingal, MA, Criswell, T, Vadhavkar, M, Dannahower, AC, Bergman, C, Zhao, W, Christ, GJ. 2012. Further development of a tissue engineered muscle repair construct in vitro for enhanced functional recovery following implantation in vivo in a murine model of volumetric muscle loss injury. Tissue Eng Part A 18:1213-28.
  5. Criswell, TL, Corona, BT, Ward, CL, Miller, M, Patel, M, Wang, Z, Christ, GJ, Soker, S. 2012. Compression-induced muscle injury in rats that mimics compartment syndrome in humans. Am J Pathol 180:787-97.
  6. Christ, GJ, Chen, AF. 2011. The grand challenge for integrative and regenerative pharmacology. Front Pharmacol 2:5.
  7. Machingal, MA, Corona, BT, Walters, TJ, Kesireddy, V, Koval, CN, Dannahower, A, Zhao, W, Yoo, JJ, Christ, GJ. 2011. A tissue-engineered muscle repair construct for functional restoration of an irrecoverable muscle injury in a murine model. Tissue Eng Part A 17:2291-303.
  8. Kanika, ND, Chang, J, Tong, Y, Tiplitsky, S, Lin, J, Yohannes, E, Tar, M, Chance, M, Christ, GJ, Melman, A, Davies, KD. 2011. Oxidative stress status accompanying diabetic bladder cystopathy results in the activation of protein degradation pathways. BJU Int 107:1676-84.
  9. Christ, GJ. 2011. Potential applications of gene therapy/transfer to the treatment of lower urinary tract diseases/disorders. Handb Exp Pharmacol :255-65.
  10. Neff, LP, Tillman, BW, Yazdani, SK, Machingal, MA, Yoo, JJ, Soker, S, Bernish, BW, Geary, RL, Christ, GJ. 2011. Vascular smooth muscle enhances functionality of tissue-engineered blood vessels in vivo. J Vasc Surg 53:426-34.
  11. Corona, BT, Ward, CL, Harrison, BS, Christ, GJ. 2010. Regenerative medicine: basic concepts, current status, and future applications. J Investig Med 58:849-58.
  12. Füllhase, C, Soler, R, Gratzke, C, Brodsky, M, Christ, GJ, Andersson, KE. 2010. Spinal effects of the fesoterodine metabolite 5-hydroxymethyl tolterodine and/or doxazosin in rats with or without partial urethral obstruction. J Urol 184:783-9.
  13. Füllhase, C, Soler, R, Gratzke, C, Brodsky, M, Christ, GJ, Andersson, KE. 2010. Urodynamic evaluation of fesoterodine metabolite, doxazosin and their combination in a rat model of partial urethral obstruction. BJU Int 106:287-93.
  14. Christ, GJ, Bushman, W, Fraser, MO. 2009. Impact of diabetes and obesity on the prostate and urethra: implications to improved bladder dysfunction understanding and treatment. J Urol 182:S38-44.
  15. Furth, ME, Christ, GJ. 2009. Regenerative pharmacology for diabetes mellitus. Mol Interv 9:171-4.
  16. Christ, GJ. 2009. Bladder tissue regeneration. J Urol 182:16-7.
  17. Yazdani, SK, Watts, B, Machingal, M, Jarajapu, YP, Van Dyke, ME, Christ, GJ. 2009. Smooth muscle cell seeding of decellularized scaffolds: the importance of bioreactor preconditioning to development of a more native architecture for tissue-engineered blood vessels. Tissue Eng Part A 15:827-40.
  18. Aboushwareb, T, Zhou, G, Deng, FM, Turner, C, Andersson, KE, Tar, M, Zhao, W, Melman, A, D'Agostino, R Jr, Sun, TT, Christ, GJ. 2009. Alterations in bladder function associated with urothelial defects in uroplakin II and IIIa knockout mice. Neurourol Urodyn 28:1028-33.
  19. Christ, GJ, Andersson, KE, Williams, K, Zhao, W, D'Agostino, R Jr, Kaplan, J, Aboushwareb, T, Yoo, J, Calenda, G, Davies, KP, Sellers, RS, Melman, A. 2009. Smooth-muscle-specific gene transfer with the human maxi-k channel improves erectile function and enhances sexual behavior in atherosclerotic cynomolgus monkeys. Eur Urol 56:1055-66.
  20. Gratzke, C, Christ, GJ, Stief, CG, Andersson, KE, Hedlund, P. 2010. Localization and function of cannabinoid receptors in the corpus cavernosum: basis for modulation of nitric oxide synthase nerve activity. Eur Urol 57:342-8.
  21. Gratzke, C, Jarajapu, YP, Christ, GJ, Kaplan, JR, Williams, JK, Andersson, KE, Badlani, G. 2008. Effects of long-term dietary soy treatment on female urethral morphology and function in ovariectomized nonhuman primates. J Urol 180:2247-53.
  22. Choi, JS, Lee, SJ, Christ, GJ, Atala, A, Yoo, JJ. 2008. The influence of electrospun aligned poly(epsilon-caprolactone)/collagen nanofiber meshes on the formation of self-aligned skeletal muscle myotubes. Biomaterials 29:2899-906.
  23. Hodges, SJ, Zhou, G, Deng, FM, Aboushwareb, T, Turner, C, Andersson, KE, Santago, P, Case, D, Sun, TT, Christ, GJ. 2008. Voiding pattern analysis as a surrogate for cystometric evaluation in uroplakin II knockout mice. J Urol 179:2046-51.
  24. Yohannes, E, Chang, J, Christ, GJ, Davies, KP, Chance, MR. 2008. Proteomics analysis identifies molecular targets related to diabetes mellitus-associated bladder dysfunction. Mol Cell Proteomics 7:1270-85.
  25. Melman, A, Biggs, G, Davies, K, Zhao, W, Tar, MT, Christ, GJ. 2008. Gene transfer with a vector expressing Maxi-K from a smooth muscle-specific promoter restores erectile function in the aging rat. Gene Ther 15:364-70.
  26. Christ, GJ, Andersson, KE. 2007. Rho-kinase and effects of Rho-kinase inhibition on the lower urinary tract. Neurourol Urodyn 26:948-54.
  27. Zotova, EG, Christ, GJ, Zhao, W, Tar, M, Kuppam, SD, Arezzo, JC. 2007. Effects of fidarestat, an aldose reductase inhibitor, on nerve conduction velocity and bladder function in streptozotocin-treated female rats. J Diabetes Complications 21:187-95.
  28. Andersson, KE, Christ, GJ. 2007. Regenerative pharmacology: the future is now. Mol Interv 7:79-86.
  29. Hipp, JD, Davies, KP, Tar, M, Valcic, M, Knoll, A, Melman, A, Christ, GJ. 2007. Using gene chips to identify organ-specific, smooth muscle responses to experimental diabetes: potential applications to urological diseases. BJU Int 99:418-430.
  30. Davies, KP, Zhao, W, Tar, M, Figueroa, JC, Desai, P, Verselis, VK, Kronengold, J, Wang, HZ, Melman, A, Christ, GJ. 2007. Diabetes-induced changes in the alternative splicing of the slo gene in corporal tissue. Eur Urol 52:1229-37.
  31. Wang, HZ, Brink, PR, Christ, GJ. 2006. Gap junction channel activity in short-term cultured human detrusor myocyte cell pairs: gating and unitary conductances. Am J Physiol Cell Physiol 291:C1366-76.
  32. Christ, GJ, Hsieh, Y, Zhao, W, Schenk, G, Venkateswarlu, K, Wang, HZ, Tar, MT, Melman, A. 2006. Effects of streptozotocin-induced diabetes on bladder and erectile (dys)function in the same rat in vivo. BJU Int 97:1076-82.
  33. Christ, GJ, Hodges, S. 2006. Molecular mechanisms of detrusor and corporal myocyte contraction: identifying targets for pharmacotherapy of bladder and erectile dysfunction. Br J Pharmacol 147 Suppl 2:S41-55.
  34. Brink, PR, Valiunas, V, Wang, HZ, Zhao, W, Davies, K, Christ, GJ. 2006. Experimental diabetes alters connexin43 derived gap junction permeability in short-term cultures of rat corporeal vascular smooth muscle cells. J Urol 175:381-6.
  35. Hassan, GS, Mukherjee, S, Nagajyothi, F, Weiss, LM, Petkova, SB, de Almeida, CJ, Huang, H, Desruisseaux, MS, Bouzahzah, B, Pestell, RG, Albanese, C, Christ, GJ, Lisanti, MP, Tanowitz, HB. 2006. Trypanosoma cruzi infection induces proliferation of vascular smooth muscle cells. Infect Immun 74:152-9.
  36. Christ, GJ. 2005. siRNA for erectile dysfunction. J Urol 174:819.
  37. Boczko, J, Tar, M, Melman, A, Jelicks, LA, Wittner, M, Factor, SM, Zhao, D, Hafron, J, Weiss, LM, Tanowitz, HB, Christ, GJ. 2005. Trypanosoma cruzi infection induced changes in the innervation, structure and function of the murine bladder. J Urol 173:1784-8.
  38. Yoshimura, N, Chancellor, MB, Andersson, KE, Christ, GJ. 2005. Recent advances in understanding the biology of diabetes-associated bladder complications and novel therapy. BJU Int 95:733-8.
  39. Tanowitz, HB, Huang, H, Jelicks, LA, Chandra, M, Loredo, ML, Weiss, LM, Factor, SM, Shtutin, V, Mukherjee, S, Kitsis, RN, Christ, GJ, Wittner, M, Shirani, J, Kisanuki, YY, Yanagisawa, M. 2005. Role of endothelin 1 in the pathogenesis of chronic chagasic heart disease. Infect Immun 73:2496-503.
  40. Christ, GJ, Liebert, M. 2005. Proceedings of the Baltimore smooth muscle meeting: identifying research frontiers and priorities for the lower urinary tract. J Urol 173:1406-9.
  41. Christ, GJ. 2004. Systems and integrative pharmacology: putting the puzzle pieces together. Mol Interv 4:240-2.
  42. Christ, GJ, Day, N, Santizo, C, Sato, Y, Zhao, W, Sclafani, T, Bakal, R, Salman, M, Davies, K, Melman, A. 2004. Intracorporal injection of hSlo cDNA restores erectile capacity in STZ-diabetic F-344 rats in vivo. Am J Physiol Heart Circ Physiol 287:H1544-53.
  43. Mukherjee, S, Huang, H, Petkova, SB, Albanese, C, Pestell, RG, Braunstein, VL, Christ, GJ, Wittner, M, Lisanti, MP, Berman, JW, Weiss, LM, Tanowitz, HB. 2004. Trypanosoma cruzi infection activates extracellular signal-regulated kinase in cultured endothelial and smooth muscle cells. Infect Immun 72:5274-82.
  44. Christ, GJ, Lue, T. 2004. Physiology and biochemistry of erections. Endocrine 23:93-100.
  45. Christ, GJ, Venkateswarlu, K, Day, NS, Valcic, M, Santizo, C, Zhao, W, Wang, HZ, Persson, K, Andersson, KE. 2003. Intercellular communication and bladder function. Adv Exp Med Biol 539:239-54.
  46. Christ, GJ. 2004. Gene therapy treatments for erectile and bladder dysfunction. Curr Urol Rep 5:52-60.
  47. Woodman, SE, Cheung, MW, Tarr, M, North, AC, Schubert, W, Lagaud, G, Marks, CB, Russell, RG, Hassan, GS, Factor, SM, Christ, GJ, Lisanti, MP. 2004. Urogenital alterations in aged male caveolin-1 knockout mice. J Urol 171:950-7.
  48. Christ, GJ. 2003. Frontiers in gene therapy for erectile dysfunction. Int J Impot Res 15 Suppl 5:S33-40.
  49. Noss, MB, Christ, GJ, Melman, A. 1999. Sildenafil: a new oral therapy for erectile dysfunction. Drugs Today (Barc) 35:211-7.
  50. Christ, GJ. 2000. K+ channels and gap junctions in the modulation of corporal smooth muscle tone. Drug News Perspect 13:28-36.
  51. Christ, GJ. 2000. Gene therapy: future strategies and therapies. Drugs Today (Barc) 36:175-84.
  52. Melman, A, Zhao, W, Davies, KP, Bakal, R, Christ, GJ. 2003. The successful long-term treatment of age related erectile dysfunction with hSlo cDNA in rats in vivo. J Urol 170:285-90.
  53. Christ, GJ. 2003. Membrane bound guanylyl cyclase as a potential molecular target for the treatment of erectile dysfunction. J Urol 169:1923.
  54. Christ, GJ, Day, NS, Day, M, Zhao, W, Persson, K, Pandita, RK, Andersson, KE. 2003. Increased connexin43-mediated intercellular communication in a rat model of bladder overactivity in vivo. Am J Physiol Regul Integr Comp Physiol 284:R1241-8.
  55. Lagaud, G, Davies, KP, Venkateswarlu, K, Christ, GJ. 2002. The physiology, pathophysiology and therapeutic potential of gap junctions in smooth muscle. Curr Drug Targets 3:427-40.
  56. Lagaud, G, Karicheti, V, Knot, HJ, Christ, GJ, Laher, I. 2002. Inhibitors of gap junctions attenuate myogenic tone in cerebral arteries. Am J Physiol Heart Circ Physiol 283:H2177-86.
  57. Christ, GJ. 2002. Gene therapy for erectile dysfunction: where is it going?. Curr Opin Urol 12:497-501.
  58. Jelicks, LA, Chandra, M, Shirani, J, Shtutin, V, Tang, B, Christ, GJ, Factor, SM, Wittner, M, Huang, H, Weiss, LM, Mukherjee, S, Bouzahzah, B, Petkova, SB, Teixeira, MM, Douglas, SA, Loredo, ML, D'Orleans-Juste, P, Tanowitz, HB. 2002. Cardioprotective effects of phosphoramidon on myocardial structure and function in murine Chagas' disease. Int J Parasitol 32:1497-506.
  59. Christ, GJ. 2002. K channels as molecular targets for the treatment of erectile dysfunction. J Androl 23:S10-9.
  60. Jelicks, LA, Chandra, M, Shtutin, V, Petkova, SB, Tang, B, Christ, GJ, Factor, SM, Wittner, M, Huang, H, Douglas, SA, Weiss, LM, Orleans-Juste, PD, Shirani, J, Tanowitz, HB. 2002. Phosphoramidon treatment improves the consequences of chagasic heart disease in mice. Clin Sci (Lond) 103 Suppl 48:267S-271S.
  61. Melman, A, Christ, GJ. 2002. The hemodynamics of erection and the pharmacotherapies of erectile dysfunction. Heart Dis 4:252-64.
  62. Woodman, SE, Park, DS, Cohen, AW, Cheung, MW, Chandra, M, Shirani, J, Tang, B, Jelicks, LA, Kitsis, RN, Christ, GJ, Factor, SM, Tanowitz, HB, Lisanti, MP. 2002. Caveolin-3 knock-out mice develop a progressive cardiomyopathy and show hyperactivation of the p42/44 MAPK cascade. J Biol Chem 277:38988-97.
  63. Venkateswarlu, K, Giraldi, A, Zhao, W, Wang, HZ, Melman, A, Spektor, M, Christ, GJ. 2002. Potassium channels and human corporeal smooth muscle cell tone: diabetes and relaxation of human corpus cavernosum smooth muscle by adenosine triphosphate sensitive potassium channel openers. J Urol 168:355-61.
  64. Spektor, M, Rodriguez, R, Rosenbaum, RS, Wang, HZ, Melman, A, Christ, GJ. 2002. Potassium channels and human corporeal smooth muscle cell tone: further evidence of the physiological relevance of the Maxi-K channel subtype to the regulation of human corporeal smooth muscle tone in vitro. J Urol 167:2628-35.
  65. Razani, B, Wang, XB, Engelman, JA, Battista, M, Lagaud, G, Zhang, XL, Kneitz, B, Hou, H Jr, Christ, GJ, Edelmann, W, Lisanti, MP. 2002. Caveolin-2-deficient mice show evidence of severe pulmonary dysfunction without disruption of caveolae. Mol Cell Biol 22:2329-44.
  66. Christ, GJ, Day, NS, Day, M, Santizo, C, Zhao, W, Sclafani, T, Zinman, J, Hsieh, K, Venkateswarlu, K, Valcic, M, Melman, A. 2001. Bladder injection of "naked" hSlo/pcDNA3 ameliorates detrusor hyperactivity in obstructed rats in vivo. Am J Physiol Regul Integr Comp Physiol 281:R1699-709.
  67. El-Awady, MK, Gad, YZ, Wen, Y, Eassawi, M, Effat, L, Amr, KS, Ismail, S, Christ, GJ. 2001. Schistosoma hematobium soluble egg antigens induce proliferation of urothelial and endothelial cells. World J Urol 19:263-6.
  68. Karicheti, V, Christ, GJ. 2001. Physiological roles for K+ channels and gap junctions in urogenital smooth muscle: implications for improved understanding of urogenital function, disease and therapy. Curr Drug Targets 2:1-20.
  69. Razani, B, Engelman, JA, Wang, XB, Schubert, W, Zhang, XL, Marks, CB, Macaluso, F, Russell, RG, Li, M, Pestell, RG, Di Vizio, D, Hou, H Jr, Kneitz, B, Lagaud, G, Christ, GJ, Edelmann, W, Lisanti, MP. 2001. Caveolin-1 null mice are viable but show evidence of hyperproliferative and vascular abnormalities. J Biol Chem 276:38121-38.
  70. Sato, Y, Rehman, J, Santizo, C, Melman, A, Christ, GJ. 2001. Significant physiological roles of ancillary penile nerves on increase in intracavernous pressure in rats: experiments using electrical stimulation of the medial preoptic area. Int J Impot Res 13:82-8.
  71. Sato, Y, Zhao, W, Christ, GJ. 2001. Central modulation of the NO/cGMP pathway affects the MPOA-induced intracavernous pressure response. Am J Physiol Regul Integr Comp Physiol 281:R269-78.
  72. Melman, A, Christ, GJ. 2001. Integrative erectile biology. The effects of age and disease on gap junctions and ion channels and their potential value to the treatment of erectile dysfunction. Urol Clin North Am 28:217-31, vii.
  73. Wang, HZ, Day, N, Valcic, M, Hsieh, K, Serels, S, Brink, PR, Christ, GJ. 2001. Intercellular communication in cultured human vascular smooth muscle cells. Am J Physiol Cell Physiol 281:C75-88.
  74. Wang, HZ, Lee, SW, Day, NS, Christ, GJ. 2001. Gap junction channel activity in cultured human bladder smooth muscle cell pairs: gating and unitary conductances. Urology 57:111.
  75. Christ, GJ, Day, NS, Santizo, C, Zhao, W, Sclafani, T, Karicheti, V, Valcic, M, Melman, A. 2001. Bladder instillation of "naked" hSlo/pcDNA3 ameliorates detrusor hyperactivity in obstructed rats in vivo. Urology 57:111.
  76. Moreno, AP, Campos de Carvalho, AC, Christ, G, Melman, A, Spray, DC. Gap junctions between human corpus cavernosum smooth muscle cells: gating properties and unitary conductance. Am J Physiol. 1993 Jan;264(1 Pt 1):C80-92. PubMed PMID: 8381593.
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