Criswell, TL, Corona, BT, Wang, Z, Zhou, Y, Niu, G, Xu, Y, Christ, GJ, Soker, S. 2013. The role of endothelial cells in myofiber differentiation and the vascularization and innervation of bioengineered muscle tissue in vivo. Biomaterials 34:140-9.
Tillman, BW, Yazdani, SK, Neff, LP, Corriere, MA, Christ, GJ, Soker, S, Atala, A, Geary, RL, Yoo, JJ. 2012. Bioengineered vascular access maintains structural integrity in response to arteriovenous flow and repeated needle puncture. J Vasc Surg 56:783-93.
Burmeister, D, AbouShwareb, T, D'Agostino, R Jr, Andersson, KE, Christ, GJ. 2012. Impact of partial urethral obstruction on bladder function: time-dependent changes and functional correlates of altered expression of Ca²⁺ signaling regulators. Am J Physiol Renal Physiol 302:F1517-28.
Corona, BT, Machingal, MA, Criswell, T, Vadhavkar, M, Dannahower, AC, Bergman, C, Zhao, W, Christ, GJ. 2012. Further development of a tissue engineered muscle repair construct in vitro for enhanced functional recovery following implantation in vivo in a murine model of volumetric muscle loss injury. Tissue Eng Part A 18:1213-28.
Criswell, TL, Corona, BT, Ward, CL, Miller, M, Patel, M, Wang, Z, Christ, GJ, Soker, S. 2012. Compression-induced muscle injury in rats that mimics compartment syndrome in humans. Am J Pathol 180:787-97.
Christ, GJ, Chen, AF. 2011. The grand challenge for integrative and regenerative pharmacology. Front Pharmacol 2:5.
Machingal, MA, Corona, BT, Walters, TJ, Kesireddy, V, Koval, CN, Dannahower, A, Zhao, W, Yoo, JJ, Christ, GJ. 2011. A tissue-engineered muscle repair construct for functional restoration of an irrecoverable muscle injury in a murine model. Tissue Eng Part A 17:2291-303.
Kanika, ND, Chang, J, Tong, Y, Tiplitsky, S, Lin, J, Yohannes, E, Tar, M, Chance, M, Christ, GJ, Melman, A, Davies, KD. 2011. Oxidative stress status accompanying diabetic bladder cystopathy results in the activation of protein degradation pathways. BJU Int 107:1676-84.
Christ, GJ. 2011. Potential applications of gene therapy/transfer to the treatment of lower urinary tract diseases/disorders. Handb Exp Pharmacol :255-65.
Corona, BT, Ward, CL, Harrison, BS, Christ, GJ. 2010. Regenerative medicine: basic concepts, current status, and future applications. J Investig Med 58:849-58.
Füllhase, C, Soler, R, Gratzke, C, Brodsky, M, Christ, GJ, Andersson, KE. 2010. Spinal effects of the fesoterodine metabolite 5-hydroxymethyl tolterodine and/or doxazosin in rats with or without partial urethral obstruction. J Urol 184:783-9.
Füllhase, C, Soler, R, Gratzke, C, Brodsky, M, Christ, GJ, Andersson, KE. 2010. Urodynamic evaluation of fesoterodine metabolite, doxazosin and their combination in a rat model of partial urethral obstruction. BJU Int 106:287-93.
Christ, GJ, Bushman, W, Fraser, MO. 2009. Impact of diabetes and obesity on the prostate and urethra: implications to improved bladder dysfunction understanding and treatment. J Urol 182:S38-44.
Yazdani, SK, Watts, B, Machingal, M, Jarajapu, YP, Van Dyke, ME, Christ, GJ. 2009. Smooth muscle cell seeding of decellularized scaffolds: the importance of bioreactor preconditioning to development of a more native architecture for tissue-engineered blood vessels. Tissue Eng Part A 15:827-40.
Aboushwareb, T, Zhou, G, Deng, FM, Turner, C, Andersson, KE, Tar, M, Zhao, W, Melman, A, D'Agostino, R Jr, Sun, TT, Christ, GJ. 2009. Alterations in bladder function associated with urothelial defects in uroplakin II and IIIa knockout mice. Neurourol Urodyn 28:1028-33.
Christ, GJ, Andersson, KE, Williams, K, Zhao, W, D'Agostino, R Jr, Kaplan, J, Aboushwareb, T, Yoo, J, Calenda, G, Davies, KP, Sellers, RS, Melman, A. 2009. Smooth-muscle-specific gene transfer with the human maxi-k channel improves erectile function and enhances sexual behavior in atherosclerotic cynomolgus monkeys. Eur Urol 56:1055-66.
Gratzke, C, Christ, GJ, Stief, CG, Andersson, KE, Hedlund, P. 2010. Localization and function of cannabinoid receptors in the corpus cavernosum: basis for modulation of nitric oxide synthase nerve activity. Eur Urol 57:342-8.
Gratzke, C, Jarajapu, YP, Christ, GJ, Kaplan, JR, Williams, JK, Andersson, KE, Badlani, G. 2008. Effects of long-term dietary soy treatment on female urethral morphology and function in ovariectomized nonhuman primates. J Urol 180:2247-53.
Choi, JS, Lee, SJ, Christ, GJ, Atala, A, Yoo, JJ. 2008. The influence of electrospun aligned poly(epsilon-caprolactone)/collagen nanofiber meshes on the formation of self-aligned skeletal muscle myotubes. Biomaterials 29:2899-906.
Hodges, SJ, Zhou, G, Deng, FM, Aboushwareb, T, Turner, C, Andersson, KE, Santago, P, Case, D, Sun, TT, Christ, GJ. 2008. Voiding pattern analysis as a surrogate for cystometric evaluation in uroplakin II knockout mice. J Urol 179:2046-51.
Yohannes, E, Chang, J, Christ, GJ, Davies, KP, Chance, MR. 2008. Proteomics analysis identifies molecular targets related to diabetes mellitus-associated bladder dysfunction. Mol Cell Proteomics 7:1270-85.
Melman, A, Biggs, G, Davies, K, Zhao, W, Tar, MT, Christ, GJ. 2008. Gene transfer with a vector expressing Maxi-K from a smooth muscle-specific promoter restores erectile function in the aging rat. Gene Ther 15:364-70.
Christ, GJ, Andersson, KE. 2007. Rho-kinase and effects of Rho-kinase inhibition on the lower urinary tract. Neurourol Urodyn 26:948-54.
Zotova, EG, Christ, GJ, Zhao, W, Tar, M, Kuppam, SD, Arezzo, JC. 2007. Effects of fidarestat, an aldose reductase inhibitor, on nerve conduction velocity and bladder function in streptozotocin-treated female rats. J Diabetes Complications 21:187-95.
Andersson, KE, Christ, GJ. 2007. Regenerative pharmacology: the future is now. Mol Interv 7:79-86.
Hipp, JD, Davies, KP, Tar, M, Valcic, M, Knoll, A, Melman, A, Christ, GJ. 2007. Using gene chips to identify organ-specific, smooth muscle responses to experimental diabetes: potential applications to urological diseases. BJU Int 99:418-430.
Davies, KP, Zhao, W, Tar, M, Figueroa, JC, Desai, P, Verselis, VK, Kronengold, J, Wang, HZ, Melman, A, Christ, GJ. 2007. Diabetes-induced changes in the alternative splicing of the slo gene in corporal tissue. Eur Urol 52:1229-37.
Wang, HZ, Brink, PR, Christ, GJ. 2006. Gap junction channel activity in short-term cultured human detrusor myocyte cell pairs: gating and unitary conductances. Am J Physiol Cell Physiol 291:C1366-76.
Christ, GJ, Hsieh, Y, Zhao, W, Schenk, G, Venkateswarlu, K, Wang, HZ, Tar, MT, Melman, A. 2006. Effects of streptozotocin-induced diabetes on bladder and erectile (dys)function in the same rat in vivo. BJU Int 97:1076-82.
Christ, GJ, Hodges, S. 2006. Molecular mechanisms of detrusor and corporal myocyte contraction: identifying targets for pharmacotherapy of bladder and erectile dysfunction. Br J Pharmacol 147 Suppl 2:S41-55.
Brink, PR, Valiunas, V, Wang, HZ, Zhao, W, Davies, K, Christ, GJ. 2006. Experimental diabetes alters connexin43 derived gap junction permeability in short-term cultures of rat corporeal vascular smooth muscle cells. J Urol 175:381-6.
Christ, GJ. 2005. siRNA for erectile dysfunction. J Urol 174:819.
Boczko, J, Tar, M, Melman, A, Jelicks, LA, Wittner, M, Factor, SM, Zhao, D, Hafron, J, Weiss, LM, Tanowitz, HB, Christ, GJ. 2005. Trypanosoma cruzi infection induced changes in the innervation, structure and function of the murine bladder. J Urol 173:1784-8.
Yoshimura, N, Chancellor, MB, Andersson, KE, Christ, GJ. 2005. Recent advances in understanding the biology of diabetes-associated bladder complications and novel therapy. BJU Int 95:733-8.
Tanowitz, HB, Huang, H, Jelicks, LA, Chandra, M, Loredo, ML, Weiss, LM, Factor, SM, Shtutin, V, Mukherjee, S, Kitsis, RN, Christ, GJ, Wittner, M, Shirani, J, Kisanuki, YY, Yanagisawa, M. 2005. Role of endothelin 1 in the pathogenesis of chronic chagasic heart disease. Infect Immun 73:2496-503.
Christ, GJ, Liebert, M. 2005. Proceedings of the Baltimore smooth muscle meeting: identifying research frontiers and priorities for the lower urinary tract. J Urol 173:1406-9.
Christ, GJ. 2004. Systems and integrative pharmacology: putting the puzzle pieces together. Mol Interv 4:240-2.
Christ, GJ, Day, N, Santizo, C, Sato, Y, Zhao, W, Sclafani, T, Bakal, R, Salman, M, Davies, K, Melman, A. 2004. Intracorporal injection of hSlo cDNA restores erectile capacity in STZ-diabetic F-344 rats in vivo. Am J Physiol Heart Circ Physiol 287:H1544-53.
Melman, A, Zhao, W, Davies, KP, Bakal, R, Christ, GJ. 2003. The successful long-term treatment of age related erectile dysfunction with hSlo cDNA in rats in vivo. J Urol 170:285-90.
Christ, GJ. 2003. Membrane bound guanylyl cyclase as a potential molecular target for the treatment of erectile dysfunction. J Urol 169:1923.
Christ, GJ, Day, NS, Day, M, Zhao, W, Persson, K, Pandita, RK, Andersson, KE. 2003. Increased connexin43-mediated intercellular communication in a rat model of bladder overactivity in vivo. Am J Physiol Regul Integr Comp Physiol 284:R1241-8.
Lagaud, G, Davies, KP, Venkateswarlu, K, Christ, GJ. 2002. The physiology, pathophysiology and therapeutic potential of gap junctions in smooth muscle. Curr Drug Targets 3:427-40.
Lagaud, G, Karicheti, V, Knot, HJ, Christ, GJ, Laher, I. 2002. Inhibitors of gap junctions attenuate myogenic tone in cerebral arteries. Am J Physiol Heart Circ Physiol 283:H2177-86.
Christ, GJ. 2002. Gene therapy for erectile dysfunction: where is it going?. Curr Opin Urol 12:497-501.
Jelicks, LA, Chandra, M, Shirani, J, Shtutin, V, Tang, B, Christ, GJ, Factor, SM, Wittner, M, Huang, H, Weiss, LM, Mukherjee, S, Bouzahzah, B, Petkova, SB, Teixeira, MM, Douglas, SA, Loredo, ML, D'Orleans-Juste, P, Tanowitz, HB. 2002. Cardioprotective effects of phosphoramidon on myocardial structure and function in murine Chagas' disease. Int J Parasitol 32:1497-506.
Christ, GJ. 2002. K channels as molecular targets for the treatment of erectile dysfunction. J Androl 23:S10-9.
Jelicks, LA, Chandra, M, Shtutin, V, Petkova, SB, Tang, B, Christ, GJ, Factor, SM, Wittner, M, Huang, H, Douglas, SA, Weiss, LM, Orleans-Juste, PD, Shirani, J, Tanowitz, HB. 2002. Phosphoramidon treatment improves the consequences of chagasic heart disease in mice. Clin Sci (Lond) 103 Suppl 48:267S-271S.
Melman, A, Christ, GJ. 2002. The hemodynamics of erection and the pharmacotherapies of erectile dysfunction. Heart Dis 4:252-64.
Woodman, SE, Park, DS, Cohen, AW, Cheung, MW, Chandra, M, Shirani, J, Tang, B, Jelicks, LA, Kitsis, RN, Christ, GJ, Factor, SM, Tanowitz, HB, Lisanti, MP. 2002. Caveolin-3 knock-out mice develop a progressive cardiomyopathy and show hyperactivation of the p42/44 MAPK cascade. J Biol Chem 277:38988-97.
Venkateswarlu, K, Giraldi, A, Zhao, W, Wang, HZ, Melman, A, Spektor, M, Christ, GJ. 2002. Potassium channels and human corporeal smooth muscle cell tone: diabetes and relaxation of human corpus cavernosum smooth muscle by adenosine triphosphate sensitive potassium channel openers. J Urol 168:355-61.
Spektor, M, Rodriguez, R, Rosenbaum, RS, Wang, HZ, Melman, A, Christ, GJ. 2002. Potassium channels and human corporeal smooth muscle cell tone: further evidence of the physiological relevance of the Maxi-K channel subtype to the regulation of human corporeal smooth muscle tone in vitro. J Urol 167:2628-35.
Razani, B, Wang, XB, Engelman, JA, Battista, M, Lagaud, G, Zhang, XL, Kneitz, B, Hou, H Jr, Christ, GJ, Edelmann, W, Lisanti, MP. 2002. Caveolin-2-deficient mice show evidence of severe pulmonary dysfunction without disruption of caveolae. Mol Cell Biol 22:2329-44.
Christ, GJ, Day, NS, Day, M, Santizo, C, Zhao, W, Sclafani, T, Zinman, J, Hsieh, K, Venkateswarlu, K, Valcic, M, Melman, A. 2001. Bladder injection of "naked" hSlo/pcDNA3 ameliorates detrusor hyperactivity in obstructed rats in vivo. Am J Physiol Regul Integr Comp Physiol 281:R1699-709.
El-Awady, MK, Gad, YZ, Wen, Y, Eassawi, M, Effat, L, Amr, KS, Ismail, S, Christ, GJ. 2001. Schistosoma hematobium soluble egg antigens induce proliferation of urothelial and endothelial cells. World J Urol 19:263-6.
Karicheti, V, Christ, GJ. 2001. Physiological roles for K+ channels and gap junctions in urogenital smooth muscle: implications for improved understanding of urogenital function, disease and therapy. Curr Drug Targets 2:1-20.
Razani, B, Engelman, JA, Wang, XB, Schubert, W, Zhang, XL, Marks, CB, Macaluso, F, Russell, RG, Li, M, Pestell, RG, Di Vizio, D, Hou, H Jr, Kneitz, B, Lagaud, G, Christ, GJ, Edelmann, W, Lisanti, MP. 2001. Caveolin-1 null mice are viable but show evidence of hyperproliferative and vascular abnormalities. J Biol Chem 276:38121-38.
Sato, Y, Rehman, J, Santizo, C, Melman, A, Christ, GJ. 2001. Significant physiological roles of ancillary penile nerves on increase in intracavernous pressure in rats: experiments using electrical stimulation of the medial preoptic area. Int J Impot Res 13:82-8.
Sato, Y, Zhao, W, Christ, GJ. 2001. Central modulation of the NO/cGMP pathway affects the MPOA-induced intracavernous pressure response. Am J Physiol Regul Integr Comp Physiol 281:R269-78.
Melman, A, Christ, GJ. 2001. Integrative erectile biology. The effects of age and disease on gap junctions and ion channels and their potential value to the treatment of erectile dysfunction. Urol Clin North Am 28:217-31, vii.
Wang, HZ, Day, N, Valcic, M, Hsieh, K, Serels, S, Brink, PR, Christ, GJ. 2001. Intercellular communication in cultured human vascular smooth muscle cells. Am J Physiol Cell Physiol 281:C75-88.
Wang, HZ, Lee, SW, Day, NS, Christ, GJ. 2001. Gap junction channel activity in cultured human bladder smooth muscle cell pairs: gating and unitary conductances. Urology 57:111.
Christ, GJ, Day, NS, Santizo, C, Zhao, W, Sclafani, T, Karicheti, V, Valcic, M, Melman, A. 2001. Bladder instillation of "naked" hSlo/pcDNA3 ameliorates detrusor hyperactivity in obstructed rats in vivo. Urology 57:111.
Moreno, AP, Campos de Carvalho, AC, Christ, G, Melman, A, Spray, DC. Gap junctions between human corpus cavernosum smooth muscle cells: gating properties and unitary conductance. Am J Physiol. 1993 Jan;264(1 Pt 1):C80-92. PubMed PMID: 8381593.